• IOMM-Lee人脑膜瘤细胞(STR鉴定正确)

    价 格:¥3000

    期 货🎊:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号☯️:BTCC-1338

    产地🩰:中国

    套 餐:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameIOMM-Lee
    SynonymsIOMM-LEE; Iomm-Lee; IOMM Lee; IOMMLEE; IntraOsseous Malignant Meningioma-Lee
    AccessionBTCC-1338
    Resource Identification InitiativeTo cite this cell line use: IOMM-Lee (BTCC-1338)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Population: Chinese.
    Doubling time: ~62 hours (PubMed=2234331); 18 hours (PubMed=25984343); 22 hours (ATCC=CRL-3370).
    Omics: Array-based CGH.
    Omics: Deep exome analysis.
    Omics: shRNA library screening.
    Derived from site: In situ; Brain; UBERON=UBERON_0000955.
    Sequence variations
    • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (DepMap).
    • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=28552950).
    DiseaseIntracranial meningioma (NCIt: C4656)
    Meningioma (ORDO: Orphanet_2495)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    HierarchyChildren:

    CVCL_HA67 (IOMM-Lee-LucNeo)
    Sex of cellMale
    Age at sampling61Y
    CategoryCancer cell line
    STR profileSource(s): ATCC

    Markers:
    AmelogeninX
    CSF1PO9,10
    D5S81811,13
    D7S82011,12
    D13S3178,9
    D16S53912,13
    TH016,7
    TPOX8,11
    vWA17,18

    Run an STR similarity search on this cell line
    Publications

    PubMed=2234331; DOI=10.1097/00006123-199009000-00008
    Lee W.-H.
    Characterization of a newly established malignant meningioma cell line of the human brain: IOMM-Lee.
    Neurosurgery 27:389-395(1990)

    PubMed=16554968; DOI=10.1007/s11060-005-9076-y
    Baia G.S., Slocum A.L., Hyer J.D., Misra A., Sehati N., VandenBerg S.R., Feuerstein B.G., Deen D.F., McDermott M.W., Lal A.
    A genetic strategy to overcome the senescence of primary meningioma cell cultures.
    J. Neurooncol. 78:113-121(2006)

    PubMed=18261772; DOI=10.1016/j.surneu.2007.06.031
    Ragel B.T., Couldwell W.T., Gillespie D.L., Wendland M.M., Whang K., Jensen R.L.
    A comparison of the cell lines used in meningioma research.
    Surg. Neurol. 70:295-307(2008)

    PubMed=25984343; DOI=10.1038/sdata.2014.35
    Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
    Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
    Sci. Data 1:140035-140035(2014)

    PubMed=28552950; DOI=10.1371/journal.pone.0178322
    Mei Y., Bi W.-Y.L., Greenwald N.F., Agar N.Y., Beroukhim R., Dunn G.P., Dunn I.F.
    Genomic profile of human meningioma cell lines.
    PLoS ONE 12:E0178322-E0178322(2017)

    PubMed=31068700; DOI=10.1038/s41586-019-1186-3
    Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    Cross-references
    Cell line databases/resourcesCell_Model_Passport; SIDM01733
    DepMap; ACH-000629
    Anatomy/cell type resourcesBTO; BTO:0004464
    Biological sample resourcesBioSample; SAMN10988414
    Cell line collections (Providers)ATCC; CRL-3370
    Chemistry resourcesPharmacoDB; IOMMLee_661_2019
    Encyclopedic resourcesWikidata; Q54897853
    Polymorphism and mutation databasesCosmic; 2516047

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