• COLO320人结肠癌细胞(STR鉴定正确)

    价 格:¥1800

    期 货:现货(冻存管发2支)

    保藏中心:BTCC

    资源编号:BTCC-1044

    产地:中国

    套 餐🧝🏿:

    T25/复苏细胞 无血清冻存液 专用完全培养基500ml 南美特级胎牛血清500ml

    详细资料说明书下载质检报告(COA)

    Cell line nameCOLO 320
    SynonymsCOLO-320; Colo-320; Colo 320; COLO #320; COLO320; Colo320; CoLo320; Co320; COLO 320F; Colorado 320
    AccessionBTCC-1044
    Resource Identification InitiativeTo cite this cell line use: COLO 320 (BTCC-1044)
    CommentsPart of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
    Part of: MD Anderson Cell Lines Project.
    Population: Caucasian.
    Doubling time: 24.19 hours (PubMed=25944804); ~38 hours (DSMZ=ACC-144).
    Microsatellite instability: Stable (MSS) (PubMed=9000147; PubMed=24042735; PubMed=25926053; PubMed=28683746).
    Omics: CNV analysis.
    Omics: Deep exome analysis.
    Omics: Deep quantitative proteome analysis.
    Omics: DNA methylation analysis.
    Omics: miRNA expression profiling.
    Omics: N-glycan profiling.
    Omics: Protein expression by reverse-phase protein arrays.
    Omics: SNP array analysis.
    Omics: Transcriptome analysis by microarray.
    Omics: Transcriptome analysis by RNAseq.
    Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
    Sequence variations
    HLA typingSource: PubMed=9023415
    Class I
    HLA-AA*24:02
    HLA-BB*14:02
    HLA-CC*08:02

    Source: PubMed=26589293
    Class I
    HLA-AA*24:02,24:02
    HLA-BB*14:02,14:02
    HLA-CC*07:01,08:02
    Genome ancestrySource: PubMed=30894373

    Origin% genome


    African0.51
    Native American2.1
    East Asian, North3.77
    East Asian, South0.13
    South Asian9.18
    European, North3.59
    European, South80.72
    DiseaseColon adenocarcinoma (NCIt: C4349)
    Species of originHomo sapiens (Human) (NCBI Taxonomy: 9606)
    HierarchyChildren:

    CVCL_0219 (COLO 320DM)
    Originate from same individualCVCL_K030 ! COLO 321
    Sex of cellFemale
    Age at sampling55Y
    CategoryCancer cell line
    STR profileSource(s): DSMZ; PubMed=25877200; PubMed=25926053; RCB

    Markers:
    AmelogeninX
    CSF1PO11
    D2S133818,25
    D3S135817
    D5S81812
    D7S8209,12
    D8S117913
    D13S31711
    D16S53911,12
    D18S5115
    D19S43316.2 (PubMed=25877200)
    17 (DSMZ)
    D21S1133.2
    FGA20
    Penta D9,12
    Penta E11 (DSMZ)
    11,13 (PubMed=25877200)
    TH019
    TPOX8,9
    vWA15,18

    Run an STR similarity search on this cell line
    Web pageshttps://tcpaportal.org/mclp/
    Publications

    PubMed=498117
    Quinn L.A., Moore G.E., Morgan R.T., Woods L.K.
    Cell lines from human colon carcinoma with unusual cell products, double minutes, and homogeneously staining regions.
    Cancer Res. 39:4914-4924(1979)

    PubMed=6277475
    Frampton R.J., Suva L.J., Eisman J.A., Findlay D.M., Moore G.E., Moseley J.M., Martin T.J.
    Presence of 1,25-dihydroxyvitamin D3 receptors in established human cancer cell lines in culture.
    Cancer Res. 42:1116-1119(1982)

    PubMed=3629545; DOI=10.1016/0049-3848(87)90273-8
    Scarlett J.D., Thurlow P.J., Connellan J.M., Louis C.J.
    Plasma-dependent and -independent mechanisms of platelet aggregation induced by human tumour cell lines.
    Thromb. Res. 46:715-726(1987)

    PubMed=9000147
    Cottu P.H., Muzeau F., Estreicher A., Flejou J.-F., Iggo R.D., Thomas G., Hamelin R.
    Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.
    Oncogene 13:2727-2730(1996)

    PubMed=9000572
    Hoang J.-M., Cottu P.H., Thuille B., Salmon R.J., Thomas G., Hamelin R.
    BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.
    Cancer Res. 57:300-303(1997)

    PubMed=9023415; DOI=10.1006/cimm.1996.1062
    Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
    HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
    Cell. Immunol. 175:101-110(1997)

    PubMed=9294210; DOI=10.1073/pnas.94.19.10330
    Ilyas M., Tomlinson I.P.M., Rowan A.J., Pignatelli M., Bodmer W.F.
    Beta-catenin mutations in cell lines established from human colorectal cancers.
    Proc. Natl. Acad. Sci. U.S.A. 94:10330-10334(1997)

    PubMed=10737795; DOI=10.1073/pnas.97.7.3352
    Rowan A.J., Lamlum H., Ilyas M., Wheeler J., Straub J., Papadopoulou A., Bicknell D.C., Bodmer W.F., Tomlinson I.P.M.
    APC mutations in sporadic colorectal tumors: a mutational 'hotspot' and interdependence of the 'two hits'.
    Proc. Natl. Acad. Sci. U.S.A. 97:3352-3357(2000)

    PubMed=11526487; DOI=10.1038/sj.onc.1204611
    Gayet J., Zhou X.-P., Duval A., Rolland S., Hoang J.-M., Cottu P.H., Hamelin R.
    Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.
    Oncogene 20:5025-5032(2001)

    PubMed=11668190; DOI=10.1177/002215540104901105
    Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
    Immunocytochemical analysis of cell lines derived from solid tumors.
    J. Histochem. Cytochem. 49:1369-1378(2001)

    PubMed=11687795; DOI=10.1038/ng754
    Snijders A.M., Nowak N.J., Segraves R., Blackwood S., Brown N., Conroy J., Hamilton G., Hindle A.K., Huey B., Kimura K., Law S., Myambo K., Palmer J., Ylstra B., Yue J.P., Gray J.W., Jain A.N., Pinkel D., Albertson D.G.
    Assembly of microarrays for genome-wide measurement of DNA copy number.
    Nat. Genet. 29:263-264(2001)

    PubMed=16854228; DOI=10.1186/1476-4598-5-29
    Bandres E., Cubedo E., Agirre X., Malumbres R., Zarate R., Ramirez N., Abajo A., Navarro A., Moreno I., Monzo M., Garcia-Foncillas J.
    Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues.
    Mol. Cancer 5:29.1-29.10(2006)

    PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192
    Janakiraman M., Vakiani E., Zeng Z.-S., Pratilas C.A., Taylor B.S., Chitale D., Halilovic E., Wilson M., Huberman K., Ricarte Filho J.C., Persaud Y., Levine D.A., Fagin J.A., Jhanwar S.C., Mariadason J.M., Lash A., Ladanyi M., Saltz L.B., Heguy A., Paty P.B., Solit D.B.
    Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
    Cancer Res. 70:5901-5911(2010)

    PubMed=22460905; DOI=10.1038/nature11003
    Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
    Nature 483:603-607(2012)

    PubMed=24042735; DOI=10.1038/oncsis.2013.35
    Ahmed D., Eide P.W., Eilertsen I.A., Danielsen S.A., Eknaes M., Hektoen M., Lind G.E., Lothe R.A.
    Epigenetic and genetic features of 24 colon cancer cell lines.
    Oncogenesis 2:e71.1-e71.8(2013)

    PubMed=25926053; DOI=10.1038/ncomms8002
    Medico E., Russo M., Picco G., Cancelliere C., Valtorta E., Corti G., Buscarino M., Isella C., Lamba S., Martinoglio B., Veronese S., Siena S., Sartore-Bianchi A., Beccuti M., Mottolese M., Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
    The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
    Nat. Commun. 6:7002.1-7002.10(2015)

    PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457
    Bazzocco S., Dopeso H., Carton-Garcia F., Macaya I., Andretta E., Chionh F., Rodrigues P., Garrido M., Alazzouzi H., Nieto R., Sanchez A., Schwartz S. Jr., Bilic J., Mariadason J.M., Arango D.
    Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment.
    Clin. Cancer Res. 21:3695-3704(2015)

    PubMed=26589293; DOI=10.1186/s13073-015-0240-5
    Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
    TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
    Genome Med. 7:118.1-118.7(2015)

    PubMed=26537799; DOI=10.1074/mcp.M115.051235
    Holst S., Deuss A.J.M., van Pelt G.W., van Vliet S.J., Garcia-Vallejo J.J., Koeleman C.A.M., Deelder A.M., Mesker W.E., Tollenaar R.A., Rombouts Y., Wuhrer M.
    N-glycosylation profiling of colorectal cancer cell lines reveals association of fucosylation with differentiation and caudal type homebox 1 (CDX1)/villin mRNA expression.
    Mol. Cell. Proteomics 15:124-140(2016)

    PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
    Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
    Characterization of human cancer cell lines by reverse-phase protein arrays.
    Cancer Cell 31:225-239(2017)

    PubMed=28683746; DOI=10.1186/s12943-017-0691-y
    Berg K.C.G., Eide P.W., Eilertsen I.A., Johannessen B., Bruun J., Danielsen S.A., Bjornslett M., Meza-Zepeda L.A., Eknaes M., Lind G.E., Myklebost O., Skotheim R.I., Sveen A., Lothe R.A.
    Multi-omics of 34 colorectal cancer cell lines -- a resource for biomedical studies.
    Mol. Cancer 16:116.1-116.16(2017)

    PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
    Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
    An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
    Cancer Res. 79:1263-1273(2019)

    PubMed=31068700; DOI=10.1038/s41586-019-1186-3
    Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
    Next-generation characterization of the Cancer Cell Line Encyclopedia.
    Nature 569:503-508(2019)

    PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
    Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
    Quantitative proteomics of the Cancer Cell Line Encyclopedia.
    Cell 180:387-402.e16(2020)

    Cross-references
    Cell line databases/resourcesCLO; CLO_0002571
    CLO; CLO_0050628
    CLDB; cl828
    CCRID; 3101HUMTCHu14
    Cell_Model_Passport; SIDM00071
    ColonAtlas; COLO%20320
    DepMap; ACH-000202
    DSMZCellDive; ACC-144
    LINCS_LDP; LCL-1174
    Anatomy/cell type resourcesBTO; BTO:0002047
    Biological sample resourcesBioSample; SAMN01821622
    BioSample; SAMN03470903
    BioSample; SAMN10988542
    Cell line collections (Providers)DSMZ; ACC-144
    RCB; RCB1193
    Chemistry resourcesChEMBL-Cells; CHEMBL3307577
    ChEMBL-Targets; CHEMBL614257
    PharmacoDB; COLO320_222_2019
    PubChem_Cell_line; CVCL_1989
    Encyclopedic resourcesWikidata; Q54814087

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